Methylhydrazine → (E)-(2,4,6-trifluorophenyl)methylidenehydrazine
反応式
[F:1][C:2]1[CH:9]=[C:8]([F:10])[CH:7]=[C:6]([F:11])[C:3]=1[CH:4]=O.C[NH:13][NH2:14]>CCOCC>[F:1][C:2]1[CH:9]=[C:8]([F:10])[CH:7]=[C:6]([F:11])[C:3]=1/[CH:4]=[N:13]/[NH2:14]参加物
4
実験手順
2,4,6-Trifluoro-benzaldehyde (x) (4.5 g, 27.3 mmol) was dissolved in Et2O, methylhydrazine was added (1.43 mL, 27.3 mmol) and the RM was stirred overnight. The solvent was evaporated and the solid residue was suspended in a mixture of pentane and EtOAc to afford after filtration the title compound as a bright yellow crystalline solid (tR 4.95 min (conditions 3), MH+=198.1).
後処理
- customThe solvent was evaporated
- additionthe solid residue was suspended in a mixture of pentane and EtOAc
- customto afford
- filtrationafter filtration the title compound as a bright yellow crystalline solid (tR 4.95 min (conditions 3), MH+=198.1)
出典と根拠
- ORDレコード
- ord-cd338e979c4d47d48408e78b4dc0922f
- 出典データセット
- uspto-grants-2014_09
- 特許番号
- US08822468B2
反応ノート
読み込み中…