Dichloromethane → 3-[8-(2,6-difluorophenyl)-2-(methylsulfinyl)-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-4-yl]-4-methyl-N-(2-phenylethyl)benzamide

反応式

[Cl:51][CH2:52][Cl:53].[F:1][c:2]1[c:3](-[n:9]2[c:10](=[O:39])[cH:11][cH:12][c:13]3[c:14]2[n:15][c:16]([S:37][CH3:38])[n:17][c:18]3-[c:19]2[cH:20][c:21]([C:22](=[O:23])[NH:24][CH2:25][CH2:26][c:27]3[cH:28][cH:29][cH:30][cH:31][cH:32]3)[cH:33][cH:34][c:35]2[CH3:36])[c:4]([F:8])[cH:5][cH:6][cH:7]1.[OH:40][O:41][C:42]([c:43]1[cH:44][c:45]([Cl:46])[cH:47][cH:48][cH:49]1)=[O:50]>>[F:1][c:2]1[c:3](-[n:9]2[c:10](=[O:39])[cH:11][cH:12][c:13]3[c:14]2[n:15][c:16]([S:37]([CH3:38])=[O:40])[n:17][c:18]3-[c:19]2[cH:20][c:21]([C:22](=[O:23])[NH:24][CH2:25][CH2:26][c:27]3[cH:28][cH:29][cH:30][cH:31][cH:32]3)[cH:33][cH:34][c:35]2[CH3:36])[c:4]([F:8])[cH:5][cH:6][cH:7]1