(S)-5-dibenzylamino-1-methylpiperidin-2-one → HCID 28064098、化合物
反応式
C([N:8](CC1C=CC=CC=1)[C@@H:9]1[CH2:14][N:13]([CH3:15])[C:12](=[O:16])[CH2:11][CH2:10]1)C1C=CC=CC=1>CO.[Pd]>[NH2:8][C@@H:9]1[CH2:14][N:13]([CH3:15])[C:12](=[O:16])[CH2:11][CH2:10]1参加物
4
実験手順
450 mg (S)-5-dibenzylamino-1-methyl-piperidin-2-one are suspended in 25 ml of methanol and hydrogenated with 150 mg Pd/C 10% under a pressure of 3 bar and at a temperature of 60° C. After 16 hours the catalyst is removed by suction filtering and the filtrate is evaporated to dryness. 190 mg of the product are obtained as an oil.
後処理
- customAfter 16 hours the catalyst is removed by suction
- filtrationfiltering
- customthe filtrate is evaporated to dryness
出典と根拠
- ORDレコード
- ord-361341bef66e4e7bbc5870aec89c9a28
- 出典データセット
- uspto-grants-2014_09
- 特許番号
- US08822474B2
反応ノート
読み込み中…