2-Cyclohexen-1-one, 4,4-dimethyl- → Cyclohexanone, 4,4-dimethyl-
反応式
[CH3:1][C:2]1([CH3:9])[CH2:7][CH2:6][C:5](=[O:8])[CH:4]=[CH:3]1>CCOC(C)=O.[Pd]>[CH3:1][C:2]1([CH3:9])[CH2:7][CH2:6][C:5](=[O:8])[CH2:4][CH2:3]1参加物
4
実験手順
A mixture of 4,4-dimethyl-2-cyclohexene-1-one (5.5 g) and 10% Pd/C (0.25 g, wet, Degussa type E101) in EtOAc (50 mL) was hydrogenated under 15 psi for 3 h at room temperature. The mixture was filtered through Celite and the filtrate was concentrated in vacuo affording the title compound as a colorless solid. 1H NMR (400 MHz, CDCl3) δ ppm 1.07 (s, 6H), 1.65 (t, J=7 Hz, 4H), 2.35 (t, J=7 Hz, 4H).
後処理
- filtrationThe mixture was filtered through Celite
- concentrationthe filtrate was concentrated in vacuo
出典と根拠
- ORDレコード
- ord-ebc8b3ee3a4e4f728cceb2cefb9e3d3b
- 出典データセット
- uspto-grants-2014_09
- 特許番号
- US08822518B2
反応ノート
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