Methyl isoeugenol → 1,2-Dimethoxy-4-propylbenzene

HRID 704000

反応式

HRID 704000 の反応式
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH:9]=[CH:10][CH3:11])=[CH:5][C:4]=1[O:12][CH3:13].[H][H]>[Pd].CO>[CH2:9]([C:6]1[CH:5]=[C:4]([O:12][CH3:13])[C:3]([O:2][CH3:1])=[CH:8][CH:7]=1)[CH2:10][CH3:11]

参加物

5

反応物 2

HCID 7128Methyl isoeugenolHCID 178418361HCID 178418361、化合物

生成物 1

HCID 1232331,2-Dimethoxy-4-propylbenzene収率 97.2%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 887Methanol溶媒

実験手順

An atmospheric pressure hydrogenation equipment was charged with 17.8 g (0.10 M) of 1,2-dimethoxy-4-propenylbenzene, 0.9 g of palladium charcoal and 350 ml of methanol and introduced with hydrogen. The reaction was continued until the absorption of hydrogen was terminated. Palladium charcoal was filtered off from the reaction mixture. The filtrate was distilled off methanol and vacuum distilled to obtain 17.5 g (0.097 M) of 4-propylveratrole as colorless transparent liquid having a boiling point of 106°-108° C./4 mmHg.

後処理

  1. customThe reaction was continued until the absorption of hydrogen
  2. customwas terminated
  3. filtrationPalladium charcoal was filtered off from the reaction mixture
  4. distillationThe filtrate was distilled off methanol and vacuum
  5. distillationdistilled

出典と根拠

ORDレコード
ord-403b7e4fe4dd478fa644cd46e92ab690
出典データセット
uspto-grants-1991_01
特許番号
US04985458

関連ノート

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