Ethyl 4-styrylpiperidine-1carboxylate → Ethyl 4-(2-phenylethyl)piperidine-1-carboxylate
反応式
[CH:1]([CH:9]1[CH2:14][CH2:13][N:12]([C:15]([O:17][CH2:18][CH3:19])=[O:16])[CH2:11][CH2:10]1)=[CH:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1>C(OCC)(=O)C.[Pd]>[C:3]1([CH2:2][CH2:1][CH:9]2[CH2:10][CH2:11][N:12]([C:15]([O:17][CH2:18][CH3:19])=[O:16])[CH2:13][CH2:14]2)[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1参加物
4
実験手順
A mixture of 0.80 g of ethyl 4-styrylpiperidine-1carboxylate and 80 mg of 10% palladium-on-carbon in ethyl acetate (40 ml) was subjected to catalytic reduction at room temperature until stopping of hydrogen absorption. The catalyst was filtered off, and the filtrate was concentrated under reduced pressure to give 0.80 g of ethyl 4-(2-phenylethyl)piperidine-1-carboxylate.
後処理
- customwas subjected to catalytic reduction at room temperature
- customuntil stopping of hydrogen absorption
- filtrationThe catalyst was filtered off
- concentrationthe filtrate was concentrated under reduced pressure
出典と根拠
- ORDレコード
- ord-72ab2d8da791486eb82bc898cecd4a57
- 出典データセット
- uspto-grants-1991_01
- 特許番号
- US04987132
反応ノート
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