4-Methoxy cinnamic acid → 3-(p-Methoxyphenyl)propionic acid

HRID 704396

反応式

HRID 704396 の反応式
[CH3:1][O:2][C:3]1[CH:13]=[CH:12][C:6]([CH:7]=[CH:8][C:9]([OH:11])=[O:10])=[CH:5][CH:4]=1.[H][H]>CO.[Pd]>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([CH2:7][CH2:8][C:9]([OH:11])=[O:10])=[CH:12][CH:13]=1

参加物

5

反応物 2

HCID 132454-Methoxy cinnamic acidHCID 178418361HCID 178418361、化合物

生成物 1

HCID 957503-(p-Methoxyphenyl)propionic acid収率 100.5%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 887Methanol溶媒

実験手順

10% Palladium-on-carbon (200 mg) was added to a solution of 5.34 g of 4-methoxycinnamic acid in methanol, and the mixture was stirred under hydrogen until hydrogen gas absorption ceased. The catalyst was filtered off, and the filtrate was concentrated under reduced pressure to give 5.43 g of 3-(4-methoxyphenyl)propionic acid.

後処理

  1. filtrationThe catalyst was filtered off
  2. concentrationthe filtrate was concentrated under reduced pressure

出典と根拠

ORDレコード
ord-267d2b1845324df4bb8b26e892935043
出典データセット
uspto-grants-1991_01
特許番号
US04987132

関連ノート

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