Hydrogen Bromide → HCID 20074353、化合物

反応式

[BrH:1].[CH2:2]([N:9]1[CH2:17][C:16]2[C:11](=[CH:12][C:13]([O:20]C)=[C:14]([O:18]C)[CH:15]=2)[CH2:10]1)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1>>[BrH:1].[CH2:2]([N:9]1[CH2:10][C:11]2[C:16](=[CH:15][C:14]([OH:18])=[C:13]([OH:20])[CH:12]=2)[CH2:17]1)[C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][CH:8]=1

参加物

反応物 2

HCID 260Hydrogen Bromide

HCID 149937372-Benzyl-5,6-dimethoxyisoindoline

生成物 1

HCID 20074353HCID 20074353、化合物収率 96.5%

実験手順

3.54 ml of 48% hydrobromic acid was added to 500 mg (1.86 mmol) of 2-benzyl-5,6-dimethoxyisoindoline, and the mixture was refluxed for 3 hours under stirring. The precipitated crystals were collected from the reaction solution, and washed with water and acetone to obtain 578 mg (yield: 96.5%) of the above identified compound as colorless prism crystals.

後処理

temperaturethe mixture was refluxed for 3 hours
customThe precipitated crystals were collected from the reaction solution
washwashed with water and acetone
customto obtain 578 mg (yield: 96.5%) of the

出典と根拠

ORDレコード: ord-302c4e8cd01d4e7bbab0ba0088e556fb
出典データセット: uspto-grants-1991_01
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04987235

反応ノート

読み込み中…

参加物