(5-Chloro-6-methoxypyridin-2-yl)[4-(methylsulfanyl)phenyl]methanol → HCID 58452560、化合物

関与物質

反応条件

反応手順

Manganese dioxide (8.34 g) was added to a solution of (5-chloro-6-methoxypyridin-2-yl)[4-(methylsulfanyl)phenyl]methanol (1.42 g) in chloroform (40 mL), and the mixture was stirred at 65° C. for one hour. The reaction solution was filtered through celite and the filtrate was concentrated. The residue was purified by silica gel column chromatography (hexane:ethyl acetate=4:1→1:1) to give the title compound as a yellow powder (1.02 g, 71%).

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