Ethyl 6-vinylpicolinate → Ethyl 6-ethylpicolinate
反応式
[CH:1]([C:3]1[N:8]=[C:7]([C:9]([O:11][CH2:12][CH3:13])=[O:10])[CH:6]=[CH:5][CH:4]=1)=[CH2:2]>C(O)C.[OH-].[OH-].[Pd+2]>[CH2:1]([C:3]1[N:8]=[C:7]([C:9]([O:11][CH2:12][CH3:13])=[O:10])[CH:6]=[CH:5][CH:4]=1)[CH3:2]参加物
4
実験手順
Ethyl 6-vinylpicolinate (4.70 g, 26.5 mmol) was dissolved in 100 mL of ethanol. To this was added 20% Pd(OH)2 on carbon (1 g, 50% water) and the mixture was stirred under a hydrogen balloon for 2 hours. The mixture was purged with nitrogen, filtered through GF/F filter paper, and the filtrate concentrated under reduced pressure to give 4.5 g (95%) of the title compound.
後処理
- customThe mixture was purged with nitrogen
- filtrationfiltered through GF/F
- filtrationfilter paper
- concentrationthe filtrate concentrated under reduced pressure
出典と根拠
- ORDレコード
- ord-4e802e33a13c464e9e2739d49752b4fd
- 出典データセット
- uspto-grants-2015_11
- 特許番号
- US09174981B2
反応ノート
読み込み中…