Tert-butyl 4-(2-hydroxyethyl)piperazine-1-carboxylate → tert-Butyl 4-(2-(3-(3-methyl-1-((6-methylpyridin-2-yl)methyl)-1H-indazol-4-ylcarbamoyl)imidazo[1,2-a]pyridin-7-yloxy)ethyl)piperazine-1-carboxylate

反応式

CC(C)([O-])C.[K+].[OH:7][CH2:8][CH2:9][N:10]1[CH2:15][CH2:14][N:13]([C:16]([O:18][C:19]([CH3:22])([CH3:21])[CH3:20])=[O:17])[CH2:12][CH2:11]1.F[C:24]1[CH:29]=[CH:28][N:27]2[C:30]([C:33]([NH:35][C:36]3[CH:44]=[CH:43][CH:42]=[C:41]4[C:37]=3[C:38]([CH3:53])=[N:39][N:40]4[CH2:45][C:46]3[CH:51]=[CH:50][CH:49]=[C:48]([CH3:52])[N:47]=3)=[O:34])=[CH:31][N:32]=[C:26]2[CH:25]=1>C1COCC1.CN1C(=O)CCC1>[CH3:53][C:38]1[C:37]2[C:41](=[CH:42][CH:43]=[CH:44][C:36]=2[NH:35][C:33]([C:30]2[N:27]3[CH:28]=[CH:29][C:24]([O:7][CH2:8][CH2:9][N:10]4[CH2:15][CH2:14][N:13]([C:16]([O:18][C:19]([CH3:22])([CH3:21])[CH3:20])=[O:17])[CH2:12][CH2:11]4)=[CH:25][C:26]3=[N:32][CH:31]=2)=[O:34])[N:40]([CH2:45][C:46]2[CH:51]=[CH:50][CH:49]=[C:48]([CH3:52])[N:47]=2)[N:39]=1