Benzonatate → HCID 131733891、化合物

HRID 709001

反応式

HRID 709001 の反応式
[Si:1]([O-:5])([O-:4])([O-:3])[O-:2].[Ca+2:6].[Ca+2].[CH3:8][CH2:9][CH2:10][CH2:11][NH:12][C:13]1[CH:14]=[CH:15][C:16]([C:19]([O:21][CH2:22][CH2:23][O:24][CH2:25][CH2:26][O:27][CH2:28][CH2:29][O:30][CH2:31][CH2:32][O:33][CH2:34][CH2:35][O:36][CH2:37][CH2:38][O:39][CH2:40][CH2:41][O:42][CH2:43][CH2:44][O:45][CH2:46][CH2:47][O:48][CH3:49])=[O:20])=[CH:17][CH:18]=1>>[CH3:8][CH2:9][CH2:10][CH2:11][NH:12][C:13]1[CH:18]=[CH:17][C:16]([C:19]([O:21][CH2:22][CH2:23][O:24][CH2:25][CH2:26][O:27][CH2:28][CH2:29][O:30][CH2:31][CH2:32][O:33][CH2:34][CH2:35][O:36][CH2:37][CH2:38][O:39][CH2:40][CH2:41][O:42][CH2:43][CH2:44][O:45][CH2:46][CH2:47][O:48][CH3:49])=[O:20])=[CH:15][CH:14]=1.[Si:1]([O-:5])([O-:4])([O-:3])[O-:2].[Ca+2:6].[Ca+2:6]

参加物

3

反応物 2

HCID 7699BenzonatateHCID 14941Dicalcium silicate

生成物 1

HCID 131733891HCID 131733891、化合物

実験手順

Using the amounts in the preceding table, the calcium silicate was mixed at slow speed in a high shear granulator (Impeller: 250 rpm; Chopper: 3200 rpm). Benzonatate was added to it at slow speed (Impeller: 250 rpm; Chopper: 3200 rpm) at a rate of approximately 7 g/minute. The benzonatate-calcium silicate adsorbate granules formed were passed through a 425 micron screen. Using the assay described in previous examples showed 60.66 wt % benzonatate based on the total weight of the benzonatate-calcium silicate adsorbate.

出典と根拠

ORDレコード
ord-a6515cd5f7ff4fed893c13188aa17a44
出典データセット
uspto-grants-2015_11
特許番号
US09180104B2

関連ノート

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