Ethyl 3-(2-methoxy-5-(methoxycarbonyloxy)phenyl)acrylate → Ethyl 3-(2-methoxy-5-(methoxycarbonyloxy)phenyl)propanoate
反応式
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([O:9][C:10]([O:12][CH3:13])=[O:11])=[CH:5][C:4]=1[CH:14]=[CH:15][C:16]([O:18][CH2:19][CH3:20])=[O:17]>CO.[Pd]>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([O:9][C:10]([O:12][CH3:13])=[O:11])=[CH:5][C:4]=1[CH2:14][CH2:15][C:16]([O:18][CH2:19][CH3:20])=[O:17]参加物
4
実験手順
To a solution of ethyl 3-(2-methoxy-5-(methoxycarbonyloxy)phenyl)acrylate (1.00 g) in methanol (3.0 mL) was added 10% palladium-activated carbon (100 mg), and the mixture was stirred for 1 hr under a hydrogen atmosphere. The reaction mixture was filtered, and the filtrate was concentrated under reduced pressure to give the title compound (800 mg) as a yellow oil. This compound was used for the next step without further purification.