Hydroxyamine hydrochloride → 2-(3,4-Dimethoxyphenoxy)-N'-hydroxyacetoimidamide
反応式
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:10]=[CH:11][C:12]=1[O:13][CH3:14])[O:6][CH2:7][C:8]#[N:9].Cl.[OH:16][NH2:17]>CO.O>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:10]=[CH:11][C:12]=1[O:13][CH3:14])[O:6][CH2:7][C:8](=[N:17][OH:16])[NH2:9]参加物
4
反応条件
- 温度
- 100 °C
実験手順
To a solution of 2-(3,4-dimethoxyphenoxy)acetonitrile (3.8 g) in MeOH—H2O (1:1), hydroxyamine hydrochloride was added and the mixture was stirred at 100° C. for 3 hours. After distilling off the solvent under reduced pressure, the residue was recovered by filtration and washed with water and hexane to give a crude form of the titled compound (4.9 g).
後処理
- distillationAfter distilling off the solvent under reduced pressure
- filtrationthe residue was recovered by filtration
- washwashed with water and hexane
出典と根拠
- ORDレコード
- ord-9ca000f3a7e144bdbd9b052e1308891e
- 出典データセット
- uspto-grants-2015_11
- 特許番号
- US09181229B2
反応ノート
読み込み中…