(2-Methoxypyridin-4-yl)methanamine → 4-(Aminomethyl)pyridin-2(1H)-one

HRID 711263

反応式

HRID 711263 の反応式
C[O:2][C:3]1[CH:8]=[C:7]([CH2:9][NH2:10])[CH:6]=[CH:5][N:4]=1>Cl>[NH2:10][CH2:9][C:7]1[CH:6]=[CH:5][NH:4][C:3](=[O:2])[CH:8]=1

参加物

3

反応物 1

HCID 16227983(2-Methoxypyridin-4-yl)methanamine

生成物 1

HCID 150793014-(Aminomethyl)pyridin-2(1H)-one

試薬・触媒・溶媒 1

HCID 313Hydrochloric Acid溶媒

実験手順

The starting material (2-methoxypyridin-4-yl)methanamine 56-2 in 3N HCl was refluxed at 110° C. for 12 hours. The reaction was taken to dryness by rotary evaporation to give crude 4-(aminomethyl)pyridin-2(1H)-one 56-3.

後処理

  1. customThe reaction was taken to dryness by rotary evaporation

出典と根拠

ORDレコード
ord-0a0113fcf18d4c1b932891df2d2f6d59
出典データセット
uspto-grants-2015_11
特許番号
US09181235B2

関連ノート

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