Ethanesulfonyl chloride → N-(4-bromo-6,7-dihydro-5H-cyclopenta[c]pyridin-7-yl)ethanesulfonamide
反応式
[Br:1][C:2]1[C:3]2[CH2:10][CH2:9][CH:8]([NH2:11])[C:4]=2[CH:5]=[N:6][CH:7]=1.[CH2:12]([S:14](Cl)(=[O:16])=[O:15])[CH3:13]>>[Br:1][C:2]1[C:3]2[CH2:10][CH2:9][CH:8]([NH:11][S:14]([CH2:12][CH3:13])(=[O:16])=[O:15])[C:4]=2[CH:5]=[N:6][CH:7]=1参加物
3
実験手順
In analogy to the procedure described for the preparation of example 2, (rac)-4-bromo-6,7-dihydro-5H-cyclopenta[c]pyridin-7-amine (intermediate A-4 [C]) and ethanesulfonyl chloride gave the title compound as a grey solid in 94% yield. MS: 304.99 (M+H+, 1 Br).
出典と根拠
- ORDレコード
- ord-ea022da9c9034ecaadb61f10116019c6
- 出典データセット
- uspto-grants-2015_11
- 特許番号
- US09187429B2
反応ノート
読み込み中…