HCID 86595355、化合物 → HCID 86595356、化合物

HRID 719740ノート

反応式

HRID 719740 の反応式
[Cl-:1].[CH3:2][N+:3]1[CH:7]=[CH:6][N:5]([CH2:8][CH:9]2[CH2:13][CH2:12][CH2:11][N:10]2[C:14]2[CH:19]=[CH:18][C:17]([N+:20]([O-])=O)=[CH:16][CH:15]=2)[CH:4]=1>C(O)C.[Pd]>[ClH:1].[Cl-:1].[NH2:20][C:17]1[CH:18]=[CH:19][C:14]([N:10]2[CH2:11][CH2:12][CH2:13][CH:9]2[CH2:8][N:5]2[CH:6]=[CH:7][N+:3]([CH3:2])=[CH:4]2)=[CH:15][CH:16]=1

参加物

4

反応物 1

HCID 86595355HCID 86595355、化合物

生成物 1

HCID 86595356HCID 86595356、化合物

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

3 g (0.093 mol) of 1-methyl-3-[1-(4-nitrophenyl)pyrrolidin-2-ylmethyl]-3H-imidazol-1-ium (2) dissolved in 350 ml of ethanol were hydrogenated in the presence of palladium-on-charcoal under a hydrogen pressure of 10 bar at a temperature of 30° C.; after filtering off the catalyst, the expected derivative (3) was isolated in the form of the hydrochloride. 2.6 g of a white powder were obtained.

後処理

  1. customat a temperature of 30° C.
  2. filtrationafter filtering off the catalyst

出典と根拠

ORDレコード
ord-002f2343ffa64d27b57423481489db5b
出典データセット
uspto-grants-2006_11
特許番号
US07132543B2

反応ノート

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