化工社化工社 化学情報印刷レポート · 研究参考用
Acetic Anhydride → 2-Pyridinemethanol, 2-acetate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetic Anhydride | HCID 7918 | — |
| 反応物 | 2-Methylpyridine 1-oxide | HCID 13602 | — |
| 溶媒 | Ethyl Acetate | HCID 8857 | — |
| 生成物 | 2-Pyridinemethanol, 2-acetate | HCID 13881 | — |
反応手順
A solution of the 2-methyl pyridine N-oxide (1.0 mmol) in acetic anhydride (5 mmol) was heated to reflux for 0.5 h. Work-up (EtOAc), drying (MgSO4), evaporation and purification by preparative TLC or flash chromatography afforded the 2-(acetoxymethyl)pyridine.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07138401B2 |
| 出典データセット | uspto-grants-2006_11 |
| ORD ID | ord-46b932fbdc8540ac87584522c6800eb6 |
| 出典メモ | uspto-grants-2006_11 |