huagongshe.com
HRID722084

反应详情

EQUATION

反应方程式

HRID 722084 的结构方程式

REACTANTS

反应物

2
结构：CC(=O)OC(C)=O
HCID7918

Acetic anhydride

C4H6O3

结构：Cc1cccc[n+]1[O-]
HCID13602

2-Methylpyridine 1-oxide

C6H7NO

PRODUCTS

生成物

1
结构：CC(=O)OCc1ccccn1
HCID13881

2-Pyridinemethanol, acetate (ester)

C8H9NO2

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCOC(C)=O
溶剂HCID8857

Ethyl acetate

C4H8O2

PROCEDURE

实验过程

A solution of the 2-methyl pyridine N-oxide (1.0 mmol) in acetic anhydride (5 mmol) was heated to reflux for 0.5 h. Work-up (EtOAc), drying (MgSO4), evaporation and purification by preparative TLC or flash chromatography afforded the 2-(acetoxymethyl)pyridine.

WORKUP

后处理

  1. temperatureto reflux for 0.5 h
  2. customdrying
  3. custom(MgSO4), evaporation and purification by preparative TLC or flash chromatography