HCID 9888078、化合物 → HCID 21873392、化合物

反応式

[CH3:1][N:2]([CH3:31])[CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([N:12]2[CH:16]=[CH:15][N:14]([C:17]3[CH:22]=[CH:21][C:20]([O:23][C:24]4[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=4)=[CH:19][CH:18]=3)[C:13]2=[O:30])=[CH:8][CH:7]=1.[H][H]>C(O)C.[OH-].[Pd+2].[OH-]>[CH3:1][N:2]([CH3:31])[CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([N:12]2[CH2:16][CH2:15][N:14]([C:17]3[CH:22]=[CH:21][C:20]([O:23][C:24]4[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=4)=[CH:19][CH:18]=3)[C:13]2=[O:30])=[CH:8][CH:7]=1

参加物

実験手順

Palladium(II) hydroxide (20 mg) was added to a solution of 1-(4-(2-dimethylaminoethoxy)phenyl]-3-(4-phenoxyphenyl)-1,3-dihydroimidazol-2-one (50 mg) in ethanol (5 mL) under nitrogen. The nitrogen atmosphere was replaced by hydrogen and the mixture was shaken for 8 hours. The catalyst was filtered off and the filtrate was concentrated. The product with the molecular weight of 417.51 (C25H27N3O3); MS (ESI): 418 ([M+H]+), was obtained in this way.