Methanol → Methyl 3-amino-4-iodobenzoate

関与物質

役割	名称	HCID	仕込み量
反応物	Methanol	HCID 887	—
反応物	Thionyl Chloride	HCID 24386	—
反応物	3-Amino-4-iodobenzoic acid	HCID 11807503	—
生成物	Methyl 3-amino-4-iodobenzoate	HCID 21628210	—

反応手順

3-Amino-4-iodobenzoic acid (13.35 g, 50.8 mmol) was added to MeOH (150 mL) and SOCl2 (4.8 mL, 65.8 mmol, 1.3 equivalent) was added. The mixture was refluxed for 3 h and then volatiles were removed under reduced pressure. The residue was co-evaporated three times with MeOH and dried in vacuo (15.23 g).

情報源と証拠

DOI	10.6084/m9.figshare.5104873.v1
特許番号	US07141574B2
出典データセット	uspto-grants-2006_11
ORD ID	ord-b5a7e02008f34cf0bac20ad17989f0b4
出典メモ	uspto-grants-2006_11