Methyl iodide → Methyl 1-methyl-4-nitro-1H-pyrrole-2-carboxylate

反応式

[N+:1]([C:4]1[CH:5]=[C:6]([C:9]([O:11][CH3:12])=[O:10])[NH:7][CH:8]=1)([O-:3])=[O:2].I[CH3:14]>>[CH3:14][N:7]1[CH:8]=[C:4]([N+:1]([O-:3])=[O:2])[CH:5]=[C:6]1[C:9]([O:11][CH3:12])=[O:10]

参加物

反応物 2

HCID 6328Methyl iodide

HCID 261887Methyl 4-nitro-1h-pyrrole-2-carboxylate

生成物 1

HCID 2759930Methyl 1-methyl-4-nitro-1H-pyrrole-2-carboxylate収率 89%

実験手順

Following the basic procedure of Example 25(d), by reacting 2.9 g (17 mmol) of methyl 4-nitro-2-pyrrolecarboxylate with 1.1 ml of iodomethane, 2.8 g (89%) of the expected compound of melting point 122°-124° C. were obtained.

出典と根拠

ORDレコード: ord-2fbddfa821b84ea3a3d13c2a3e429680
出典データセット: uspto-grants-1998_01
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05709867

反応ノート

読み込み中…