1-Iodopropane → methyl N-propyl-4-nitro-2-pyrrolecarboxylate

反応式

[N+:1]([C:4]1[CH:5]=[C:6]([C:9]([O:11][CH3:12])=[O:10])[NH:7][CH:8]=1)([O-:3])=[O:2].I[CH2:14][CH2:15][CH3:16]>>[CH2:14]([N:7]1[CH:8]=[C:4]([N+:1]([O-:3])=[O:2])[CH:5]=[C:6]1[C:9]([O:11][CH3:12])=[O:10])[CH2:15][CH3:16]

参加物

反応物 2

HCID 336431-Iodopropane

HCID 261887Methyl 4-nitro-1h-pyrrole-2-carboxylate

生成物 1

HCID 18792294methyl N-propyl-4-nitro-2-pyrrolecarboxylate収率 64%

実験手順

Following the basic procedure of Example 25(d), by reacting 1.79 g (10.5 mmol) of methyl 4-nitro-2-pyrrolecarboxylate with 1.23 ml (12.6 mmol) of 3-iodopropane, 1.42 g (64%) of the expected compound was obtained.

出典と根拠

ORDレコード: ord-07f1b3a29cdc420f8fed762226a1d319
出典データセット: uspto-grants-1998_01
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05709867

反応ノート

読み込み中…