Ethyl Acetate → HCID 19707473、化合物
反応式
[O:1]([C:8]1[CH:15]=[CH:14][C:11]([CH:12]=O)=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Li][CH2:17][CH2:18][CH2:19][CH3:20].C(OCC)(=[O:23])C.C([O-])(O)=O.[Na+]>C1COCC1.CCCCCC>[OH:23][CH2:17][CH2:18][CH2:19][CH2:20][CH2:12][C:11]1[CH:14]=[CH:15][C:8]([O:1][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)=[CH:9][CH:10]=1参加物
7
実験手順
To a solution of 4-phenoxybenzaldehyde (704 mg, 3.56 mmol) in 15 mL of THF at -78° C. was added n-BuLi dropwise (3.73 mmol, 2.5M in hexane). After 24 hours, the reaction was poured into ethyl acetate and sat. aq. NaHCO3 solution, then washed with brine, dried (Na2SO4) and concentrated in vacuo to provide the crude product.
後処理
- washwashed with brine
- dry with materialdried (Na2SO4)
- concentrationconcentrated in vacuo
出典と根拠
- ORDレコード
- ord-0b16357306bf43d9bafdbd5422b3dd0e
- 出典データセット
- uspto-grants-1998_01
- 特許番号
- US05710171
反応ノート
読み込み中…