1-Chloro-2-iodobenzene → Hydrochloric Acid

HRID 727212

反応式

HRID 727212 の反応式
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1I.[Mg].C1O[C:13]2([CH2:18][CH2:17][C:16](=O)[CH2:15][CH2:14]2)[O:12]C1>O1CCCC1>[ClH:1].[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:16]1[CH2:17][CH2:18][C:13](=[O:12])[CH2:14][CH:15]=1

参加物

6

反応物 3

HCID 119931-Chloro-2-iodobenzeneHCID 5674151,4-Dioxaspiro[4.5]decan-8-oneHCID 5462224Magnesium

生成物 2

HCID 313Hydrochloric Acid収率 10%HCID 197051921-(2-Chlorophenyl)-1-cyclohexen-4-one

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

実験手順

This compound is prepared in a manner analogous to that of Step D of Example 7, using 9.5 grams (0.040 mole) of 1-chloro-2-iodobenzene, 1.1 grams (0.044 mole) of magnesium turnings, 6.2 grams (0.040 mole) of 1,4-cyclohexanedione mono-ethylene ketal, and about 1 00 mL of aqueous 10% hydrochloric acid in about 95 mL of tetrahydrofuran, yielding 1-(2-chlorophenyl)-1-cyclohexen-4-one.

後処理

  1. customThis compound is prepared in a manner analogous to that of Step D of Example 7

出典と根拠

ORDレコード
ord-ca7d2fa62cc34f8899d956b2b416cfbb
出典データセット
uspto-grants-1998_01
特許番号
US05712281

関連ノート

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