Hydrochloric Acid → 2-Amino-5-bromo-3-iodobenzenesulphonic acid

HRID 727435

反応式

HRID 727435 の反応式
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([Br:8])=[CH:4][C:3]=1[S:9]([OH:12])(=[O:11])=[O:10].[I:13]Cl.Cl>CO>[NH2:1][C:2]1[C:7]([I:13])=[CH:6][C:5]([Br:8])=[CH:4][C:3]=1[S:9]([OH:12])(=[O:11])=[O:10]

参加物

5

反応物 3

HCID 313Hydrochloric AcidHCID 24640Iodine chlorideHCID 150236152-Amino-5-bromobenzenesulphonic acid

生成物 1

HCID 189193852-Amino-5-bromo-3-iodobenzenesulphonic acid

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

反応条件

温度
90 °C

実験手順

To 45 g (176 mmol) of 2-amino-5-bromobenzenesulphonic acid are added 46 g (282 mmol) of iodine chloride, 400 ml of aqueous 1N hydrochloric acid solution and 400 ml of methanol. The mixture is heated at 90° C. for 18 hours and concentrated under reduced pressure, and the residue is crystallized from ethanol.

後処理

  1. concentrationconcentrated under reduced pressure
  2. customthe residue is crystallized from ethanol

出典と根拠

ORDレコード
ord-c7555d9d61194faeb8c71463882c07bf
出典データセット
uspto-grants-1998_01
特許番号
US05712393

関連ノート

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