m-Chloroperbenzoic acid → 2-(4,4'-Difluorobenzhydrylidene)-1,3,5-trithiane-5-oxide
反応式
[F:1][C:2]1[CH:21]=[CH:20][C:5]([C:6](=[C:14]2[S:19][CH2:18][S:17][CH2:16][S:15]2)[C:7]2[CH:12]=[CH:11][C:10]([F:13])=[CH:9][CH:8]=2)=[CH:4][CH:3]=1.ClC1C=CC=C(C(OO)=[O:30])C=1>ClCCl>[F:13][C:10]1[CH:9]=[CH:8][C:7]([C:6](=[C:14]2[S:15][CH2:16][S:17](=[O:30])[CH2:18][S:19]2)[C:5]2[CH:20]=[CH:21][C:2]([F:1])=[CH:3][CH:4]=2)=[CH:12][CH:11]=1参加物
4
実験手順
To a 30 ml of dichloromethane of 1.5 g of 2-(4,4'-difluorobenzhydrylidene)-1,3,5-trithiane was added 0.77 g of m-chloroperbenzoic acid in small portions at 0° C., and the resulting mixture was stirred overnight. After completion of the reaction, the reaction mixture was poured into ice-water and extracted with dichloromethane. Usual work up gave crude solid, which was purified by a silica gel column chromatography (chloroform:hexane=3:1) to obtain 1.2 g of white crystals.