Iodine → 1,9-Dimethylphenothiazin-5-ium iodide

HRID 72815

反応式

HRID 72815 の反応式
[CH3:1][C:2]1[C:15]2[NH:14][C:13]3[C:8](=[CH:9][CH:10]=[CH:11][C:12]=3[CH3:16])[S:7][C:6]=2[CH:5]=[CH:4][CH:3]=1.[I:17]I>C(Cl)(Cl)Cl>[I-:17].[CH3:16][C:12]1[C:13]2[C:8](=[S+:7][C:6]3[C:15]([N:14]=2)=[C:2]([CH3:1])[CH:3]=[CH:4][CH:5]=3)[CH:9]=[CH:10][CH:11]=1

参加物

4

反応物 2

HCID 807IodineHCID 674644911,9-dimethyl-10H-phenothiazine

生成物 1

HCID 890773051,9-Dimethylphenothiazin-5-ium iodide

試薬・触媒・溶媒 1

HCID 6212Chloroform溶媒2 回

実験手順

1,9-Dimethylphenothiazine (4.2026 g, 18.49 mmol) was dissolved in 130 mL of chloroform and crushed iodine (14.1 g, 55.55 mmol, 3 eq.) dissolved in 520 mL of chloroform was added over 2 hurs. Once newly formed precipitate was filtered off or the solvent removed under vacuum, the resulting iodide salt was stirred with ether or hexane (sometimes overnight) to remove excess iodine then refiltered. After pumping down under vacuum, a brown precipitate was obtained as product (12.6 g).

後処理

  1. additionwas added over 2 hurs
  2. filtrationOnce newly formed precipitate was filtered off
  3. customthe solvent removed under vacuum
  4. customto remove excess iodine
  5. customa brown precipitate was obtained as product (12.6 g)

出典と根拠

ORDレコード
ord-cedc4d50e13a4c5098b83e0fbcb6f8ee
出典データセット
uspto-grants-2014_09
特許番号
US08828986B2

関連ノート

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