Boron tribromide → 4-Bromocatechol
反応式
[Br:1][C:2]1[CH:3]=[C:4]([O:10]C)[C:5]([O:8]C)=[CH:6][CH:7]=1.B(Br)(Br)Br>ClCCl>[Br:1][C:2]1[CH:3]=[C:4]([OH:10])[C:5](=[CH:6][CH:7]=1)[OH:8]参加物
4
実験手順
6.51 g (0.0300 mol) of 4-bromoveratrole is dissolved in 50 ml of dichloromethane. To this suspension is added 37.6 g (0.150 mol) of boron tribromide at 0° C. The mixture was stirred for 3 hours at room temperature. Solvents were removed under reduced pressure. The resulting brown oil was dissolved in ethyl acetate and filtered through a pad of silica gel. The filtrate was concentrated to afford 5.45 g of 4-bromo catechol as a light brown oil.
後処理
- customSolvents were removed under reduced pressure
- dissolutionThe resulting brown oil was dissolved in ethyl acetate
- filtrationfiltered through a pad of silica gel
- concentrationThe filtrate was concentrated
出典と根拠
- ORDレコード
- ord-a93b7e37498b498d9f1c912a40155f65
- 出典データセット
- uspto-grants-2009_09
- 特許番号
- US07582637B2
反応ノート
読み込み中…