Ammonia → Ammonia

HRID 730473

反応式

HRID 730473 の反応式
[Na].[NH2:2][C:3]1[CH:8]=[CH:7][C:6]([N+:9]([O-:11])=[O:10])=[CH:5][C:4]=1[S:12]([OH:15])(=O)=[O:13].S(Cl)(Cl)(=O)=O.P(Cl)(Cl)(Cl)=O.S1(CCCC1)(=O)=O.[NH3:33]>CO>[NH3:2].[NH2:2][C:3]1[CH:8]=[CH:7][C:6]([N+:9]([O-:11])=[O:10])=[CH:5][C:4]=1[S:12]([NH2:33])(=[O:15])=[O:13]

参加物

9

反応物 6

HCID 222AmmoniaHCID 24648Sulfuryl chlorideHCID 24813Phosphorus oxychlorideHCID 31347SulfolaneHCID 66786Benzenesulfonic acid, 2-amino-5-nitro-HCID 5360545Sodium

生成物 2

HCID 222AmmoniaHCID 153583862-Amino-5-nitrobenzenesulfonamide

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

The commercially available sodium salt of 2-amino-5-nitro-benzenesulfonic acid can be converted to the corresponding sulfonyl chloride with phosphoryl chloride in the presence of a suitable co-solvent, such as sulfolane. Treatment with ammonia, e.g., ammonia solution in methanol or ammonia gas, affords the desired 2-amino-5-nitro-benzenesulfonamide intermediate.

出典と根拠

ORDレコード
ord-0531f833112e468eaba84e598a136d32
出典データセット
uspto-grants-2009_09
特許番号
US07582754B2

関連ノート

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