Thionyl Chloride → 5-Bromo-1-chloro-2,3-dihydro-1H-indene

HRID 731181ノート

反応式

HRID 731181 の反応式
[Br:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[CH:7](O)[CH2:6][CH2:5]2.S(Cl)([Cl:14])=O>C(Cl)Cl>[Br:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[CH:7]([Cl:14])[CH2:6][CH2:5]2

参加物

4

反応物 2

HCID 24386Thionyl ChlorideHCID 134862995-bromo-2,3-dihydro-1H-inden-1-ol

生成物 1

HCID 223495155-Bromo-1-chloro-2,3-dihydro-1H-indene

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

A mixture of 47.2 (11.1 mmol) and thionyl chloride (44 mmol) in DCM (20 mL) was stirred at room temperature overnight. After evaporation of solvent, 47.3 was obtained and it was used without further purification.

後処理

  1. customAfter evaporation of solvent
  2. custom47.3 was obtained
  3. customit was used without further purification

出典と根拠

ORDレコード
ord-5026e2f771874f2087328fd253aa1a6f
出典データセット
uspto-grants-2009_09
特許番号
US07582803B2

反応ノート

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