Isoamyl Nitrite → HCID 53419315、化合物
反応式
N[C:2]1[C:6]([C:7]([O:9][CH2:10][CH3:11])=[O:8])=[CH:5][N:4]([C:12]2[CH:17]=[CH:16][CH:15]=[C:14]([Br:18])[CH:13]=2)[N:3]=1.C(ON=O)CC(C)C>C1COCC1>[CH2:10]([O:9][C:7]([C:6]1[CH:2]=[N:3][N:4]([C:12]2[CH:17]=[CH:16][CH:15]=[C:14]([Br:18])[CH:13]=2)[CH:5]=1)=[O:8])[CH3:11]参加物
4
実験手順
To a solution of the ester from Step 1 (0.5 g, 1.61 mmol) in THF (4.3 mL) was added isoamylnitrite (0.434 mL, 3.23 mmol), and the mixture was refluxed for 16 hours. It was cooled to room temperature, concentrated, dried and used as such for the subsequent step without any purification.
後処理
- temperaturethe mixture was refluxed for 16 hours
- concentrationconcentrated
- customdried
- customwithout any purification
出典と根拠
- ORDレコード
- ord-37887dfd4d7249bfaa4acf1cd72e031b
- 出典データセット
- uspto-grants-2009_09
- 特許番号
- US07589116B2
反応ノート
読み込み中…