HCID 57842780、化合物 → HCID 57842589、化合物
反応式
C(O[C:9]([N:11](C)[CH2:12][CH2:13][C:14]1[CH:19]=[CH:18][C:17]([CH:20]([NH:24][C:25]2[CH:30]=[CH:29][CH:28]=[C:27]([C:31](=[O:33])[NH2:32])[CH:26]=2)[C:21]([OH:23])=[O:22])=[CH:16][CH:15]=1)=O)C1C=CC=CC=1>[Pd]>[C:31]([C:27]1[CH:26]=[C:25]([NH:24][CH:20]([C:17]2[CH:16]=[CH:15][C:14]([CH2:13][CH2:12][NH:11][CH3:9])=[CH:19][CH:18]=2)[C:21]([OH:23])=[O:22])[CH:30]=[CH:29][CH:28]=1)(=[O:33])[NH2:32]参加物
3
実験手順
A solution of 28E (265 mg, 0.39 mmol) and Pd/C (10%, 40 mg) was stirred under H2 (1 atm) for 15 h. The reaction was filtered through Celite and concentrated to yield 28F (126 mg, 99%) as a yellow oil. MS (ESI) m/z 328.29 (M+H)+.
後処理
- filtrationThe reaction was filtered through Celite
- concentrationconcentrated
出典と根拠
- ORDレコード
- ord-40523e5dc0b44e14a78a7c7632463bba
- 出典データセット
- uspto-grants-2009_09
- 特許番号
- US07592331B2
反応ノート
読み込み中…