2-(2-Fluorophenyl)ethylamine → N-{[4-(dodecyloxy)-1-naphthyl]methyl}-N-[2-(2-fluorophenyl)-ethyl]amine

HRID 735993

反応式

HRID 735993 の反応式
[CH2:1]([O:13][C:14]1[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[C:17]([CH:24]=O)=[CH:16][CH:15]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].[F:26][C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][C:28]=1[CH2:33][CH2:34][NH2:35]>>[CH2:1]([O:13][C:14]1[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[C:17]([CH2:24][NH:35][CH2:34][CH2:33][C:28]2[CH:29]=[CH:30][CH:31]=[CH:32][C:27]=2[F:26])=[CH:16][CH:15]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]

参加物

3

反応物 2

HCID 6433572-(2-Fluorophenyl)ethylamineHCID 858412014-(Dodecyloxy)-1-naphthaldehyde

生成物 1

HCID 67186944N-{[4-(dodecyloxy)-1-naphthyl]methyl}-N-[2-(2-fluorophenyl)-ethyl]amine

実験手順

The same procedure as employed in the preparation of Example 394 (step b) but using 4-(dodecyloxy)-1-naphthaldehyde and 2-(2-fluorophenyl)ethylamine gave the title compound as an oil. HPLC (Condition A), Rt: 5.48 min (HPLC purity: 86.4%).

後処理

  1. customThe same procedure as employed in the preparation of Example 394 (step b)

出典と根拠

ORDレコード
ord-ff4a2adcda6c47f987636c761d7ec7eb
出典データセット
uspto-grants-2009_09
特許番号
US07592477B2

関連ノート

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