1-Chloro-4-(trifluoromethyl)benzene → 4-methyl-N-(4-(trifluoromethyl)phenyl)aniline

HRID 737350

反応式

HRID 737350 の反応式
Cc1ccc(N)cc1.FC(F)(F)c1ccc(Cl)cc1>CC(C)c1cc(C(C)C)c(-c2ccccc2[P](C2CCCCC2)(C2CCCCC2)->[Pd]2(<-[NH2]c3ccccc3-c3cccc[c]32)[O]S(=O)(=O)C(F)(F)F)c(C(C)C)c1.CCN=P(N=P(N(C)C)(N(C)C)N(C)C)(N(C)C)N(C)C.CCOC(=O)c1cc(C)on1.CS(C)=O>Cc1ccc(Nc2ccc(C(F)(F)F)cc2)cc1

参加物

7

反応物 2

HCID 73941-Chloro-4-(trifluoromethyl)benzeneHCID 7813p-Toluidine

生成物 1

HCID 187127994-methyl-N-(4-(trifluoromethyl)phenyl)aniline収率 22.166%

試薬・触媒・溶媒 4

HCID 76677Ethyl 5-methylisoxazole-3-carboxylate試薬HCID 33931062,N'3,N'3,N3,N3,N'5,N'5,N5,N5-nonamethyl-2,4,6-triaza-3lambda5,5lambda5-diphosphaocta-3,5-diene-3,3,5,5-tetramine試薬HCID 178439018HCID 178439018、化合物触媒HCID 679Dimethyl Sulfoxide溶媒5 回

反応条件

温度
60 °C

実験手順

These solutions were added to a 384- well source plate (80 µL per well). The Mosquito HTS liquid handling robot was used to dose each of these solutions (200 nL each) into a 1536-well plate.

後処理

  1. addition手順は記録されていません

出典と根拠

ORDレコード
ord-15078f42d6c545dbae57e7831a14f5dd
出典データセット
Ahneman

関連ノート

読み込み中…