Glycerol → HCID 86639486、化合物

HRID 74133

反応式

HRID 74133 の反応式
[CH2:1]([CH:3]([CH2:6][CH2:7][CH2:8][CH3:9])[CH:4]=[O:5])[CH3:2].[OH:10][CH2:11][CH:12]([CH2:14][OH:15])[OH:13]>[Pd]>[CH2:1]([CH:3]([CH2:6][CH2:7][CH2:8][CH3:9])[CH:4]=[O:5])[CH3:2].[OH:10][CH2:11][CH:12]([CH2:14][OH:15])[OH:13]

参加物

4

反応物 2

HCID 753GlycerolHCID 312412-Ethylhexanal

生成物 1

HCID 86639486HCID 86639486、化合物

試薬・触媒・溶媒 1

HCID 23938Palladium触媒

反応条件

温度
200 °C

実験手順

2-Ethylhexanal (12.8 g, 15.6 ml, 0.1 mol), glycerol (92.09 g, 73.7 ml, 1 mol), and 10% Pd/C (5 wt %, 0.64 g) are charged to a Parr reactor, purged with nitrogen three times, heated to 200° C. with stirring and run at 1000 psi of hydrogen for 7 hrs. The reaction mixture forms two phases upon cooling. GC analysis of each phase shows complete consumption of 2-ethylhexanal. Bottom phase (glycerol): glycerol monoethers 3-(2-ethyl)hexoxy-1,2-propanediol and 2-(2-ethyl)hexoxy-1,2-propanediol (55.4%, ratio 13.6), glycerol diethers 1,3-di(2-ethy)hexoxy-2-propanol and 2,3-di(2-ethyl)hexoxy-1-propanol (24.7%), 2-ethyhexanol (3.2%). Top phase (crude product): glycerol monoethers 3-di(2-ethyl)hexoxy-1,2-propanediol and 2-di(2-ethyl)hexoxy-1,2-propanediol (55%, ratio 12.8), glycerol diethers 1,3-di(2-ethy)hexoxy-2-propanol and 2,3-di(2-ethyl)hexoxy-1-propanol (24.8%), 2-ethylhexanol (3.5%).

後処理

  1. custompurged with nitrogen three times
  2. temperatureThe reaction mixture forms two phases upon cooling
  3. customconsumption of 2-ethylhexanal

出典と根拠

ORDレコード
ord-61d19bc0797f40adb22ac54398cf3f65
出典データセット
uspto-grants-2014_09
特許番号
US08829229B2

関連ノート

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