Glycerol → 2-Pentanone Glycerol

HRID 74136

反応式

HRID 74136 の反応式
[CH3:1][C:2](=[O:6])[CH2:3][CH2:4][CH3:5].[OH:7][CH2:8][CH:9]([CH2:11][OH:12])[OH:10]>[Pd]>[CH3:1][C:2](=[O:6])[CH2:3][CH2:4][CH3:5].[OH:7][CH2:8][CH:9]([CH2:11][OH:12])[OH:10]

参加物

4

反応物 2

HCID 753GlycerolHCID 78952-Pentanone

生成物 1

HCID 866394882-Pentanone Glycerol

試薬・触媒・溶媒 1

HCID 23938Palladium触媒

反応条件

温度
200 °C

実験手順

2-Pentanone (8.61 g, 10.6 ml, 0.1 mol), glycerol (92.09 g, 73.7 ml, 1 mol), and 10% Pd/C (5 wt %, 0.43 g) are charged to a Parr reactor, purged with nitrogen, heated to 200° C. with stirring and run at 1000 psi of hydrogen for 4 hrs. GC analysis reveals 92% conversion of 2-pentanone and shows selectivity to 3-sec-pentoxy-1,2-propanediol and 2-sec-pentoxy-1,3-propanediol (76.2%, isomer ratio 32.1), 1,3-di-sec-pentoxy-2-propanol (6.1%), 2-pentanol (6.9%), 4-hydroxymethyl-2-methyl-2-propyl-1,3-dioxolane (cyclic ketal) (6.7%).

後処理

  1. custompurged with nitrogen

出典と根拠

ORDレコード
ord-1c4733d399934dbc80057c570eae7071
出典データセット
uspto-grants-2014_09
特許番号
US08829229B2

関連ノート

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