Tetrabutylammonium Fluoride → 2-Cyano-4-(3-furyl)-7-mercaptonaphthalene
反応式
[C:1]([C:3]1[CH:4]=[C:5]([C:20]2[CH:24]=[CH:23][O:22][CH:21]=2)[C:6]2[C:11]([CH:12]=1)=[CH:10][C:9]([S:13]CC[Si](C)(C)C)=[CH:8][CH:7]=2)#[N:2].[N+](CCCC)(CCCC)(CCCC)CCCC.[F-]>CN(C=O)C.C1COCC1.Cl>[C:1]([C:3]1[CH:4]=[C:5]([C:20]2[CH:24]=[CH:23][O:22][CH:21]=2)[C:6]2[C:11]([CH:12]=1)=[CH:10][C:9]([SH:13])=[CH:8][CH:7]=2)#[N:2]参加物
6
実験手順
The product from Step 1 (1.8 g) was dissolved in DMF (40 mL) and there was added n-Bu4NF (1M) in THF (15 mL). The resulting mixture was stirred at r.t. for 1.5 h, diluted with 1N aqueous HCl (40 mL) then H2O (300 mL) and filtered to afford the title thiol (1.06 g) as a light orange solid m.p.: 144°-146° C.
後処理
- filtrationH2O (300 mL) and filtered
出典と根拠
- ORDレコード
- ord-a737a7ab637e4d72a3fcf62e015646b0
- 出典データセット
- uspto-grants-1996_09
- 特許番号
- US05552437
反応ノート
読み込み中…