alpha-Hydroxyacetophenone → Flavonol

HRID 742080

反応式

HRID 742080 の反応式
[C:1]1(C2C=CC=CC=2)[CH:6]=[CH:5][C:4]([CH:7]=[O:8])=[CH:3][CH:2]=1.[OH:15][CH2:16][C:17]([C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)=[O:18]>C(O)C.[OH-].[Na+]>[OH:15][C:16]1[C:7](=[O:8])[C:4]2[C:3](=[CH:2][CH:1]=[CH:6][CH:5]=2)[O:18][C:17]=1[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1

参加物

5

反応物 2

HCID 68490alpha-HydroxyacetophenoneHCID 76689(1,1'-Biphenyl)-4-carboxaldehyde

生成物 1

HCID 11349Flavonol

試薬・触媒・溶媒 2

HCID 702Ethanol溶媒2 回HCID 14798Sodium Hydroxide溶媒2 回

実験手順

180 mg of 4'-vinyl, 4-biphenyl aldehyde was mixed with 0.3 ml of 2-hydroxyacetophenone in 30 ml of ethanol. In a separate flask, 2.0 gms of NaOH was dissolved in 10 ml of aq. ethyl alcohol (50%). An NaOH solution was slowly added to the aldehyde solution. The resulting solution slowly changed its color from green to yellow to dark red. The rest of the reaction was carried out according to the method described in Example 1(b) above, producing 4'styryl, 3-hydroxyflavone.

出典と根拠

ORDレコード
ord-21ed05cb9ada411cb768795976d60d3f
出典データセット
uspto-grants-1996_09
特許番号
US05552551

関連ノート

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