Triethylamine → HCID 11207147、化合物
反応式
[F:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]=[C:9]=[S:10])=[CH:4][CH:3]=1.[CH2:11]([NH:13][CH2:14][C:15](O)=[O:16])[CH3:12].C(N(CC)CC)C>C(Cl)(Cl)Cl>[CH2:11]([N:13]1[CH2:14][C:15](=[O:16])[N:8]([C:5]2[CH:6]=[CH:7][C:2]([F:1])=[CH:3][CH:4]=2)[C:9]1=[S:10])[CH3:12]参加物
5
実験手順
The title compound was prepared by the procedure described in Example 16 using 7.65 g of 4-fluorophenyl-isothiocyanate, 9.32 g of N-ethyl glycine, 10 g of triethyl amine, and 250 mL of chloroform. Purification was achieved through crystallization from ethanol. The title compound (6.6 g) was obtained as a pink solid, m.p. 149°-151° C. Anal. Calcd. for. C11H11F N2O S: C, 55.45; H, 4.65; N, 11.76. Found: C, 55.31; H, 4.51; N, 10.82. Mass spectrum (EI, M.+) m/z 238.
後処理
- customThe title compound was prepared by the procedure
- customPurification
- customwas achieved through crystallization from ethanol
出典と根拠
- ORDレコード
- ord-835b6c83cd934335a30079f919c14639
- 出典データセット
- uspto-grants-1996_09
- 特許番号
- US05554607
反応ノート
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