Water → 6-Butylbenzo[b]quinolizinium perchlorate

HRID 742490ノート

反応式

HRID 742490 の反応式
[Cl:1]([O-:5])(=[O:4])(=[O:3])=[O:2].CO[C:8]1[C:17]2[CH:16]=[C:15]3[CH:18]=[CH:19][CH:20]=[CH:21][C:14]3=[CH:13][N+:12]=2[CH:11]=[CH:10][CH:9]=1.O.Cl([O-])(=O)(=O)=O.[Na+]>Br>[Cl:1]([O-:5])(=[O:4])(=[O:3])=[O:2].[CH2:17]([C:13]1[N+:12]2[CH:11]=[CH:10][CH:9]=[CH:8][C:17]=2[CH:16]=[C:15]2[CH:18]=[CH:19][CH:20]=[CH:21][C:14]=12)[CH2:8][CH2:9][CH3:10]

参加物

5

反応物 3

HCID 962WaterHCID 522606Sodium PerchlorateHCID 151862871-Methoxybenzo[b]quinolizinium perchlorate

生成物 1

HCID 190474766-Butylbenzo[b]quinolizinium perchlorate収率 156.2%

試薬・触媒・溶媒 1

HCID 260Hydrogen Bromide溶媒

反応条件

温度
100 °C

実験手順

A mixture of 1-methoxybenzo[b]quinolizinium perchlorate (1.4 g; 6.1 mmol) in 30 ml of 48% HBr was heated at 100° C. for 16 hour. The reaction mixture was poured into 100 ml of water and 50 ml of sodium perchlorate was added with stirring. The resulting solid was filtered and dried to afford 1.6 g (88.8%) of 1-hydroxybenzo[b]quinolizinium perchlorate (Formula II: R1 =1--OH; R2 =R3 =H; X- =ClO4-) as a solid.

後処理

  1. additionwas added
  2. filtrationThe resulting solid was filtered
  3. customdried

出典と根拠

ORDレコード
ord-0f48b2e88a4f4342a5d0d207fe20ae8c
出典データセット
uspto-grants-1996_09
特許番号
US05554620

反応ノート

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