Benzoate → Benzoate maleate

HRID 7455

反応式

HRID 7455 の反応式
[C:1]([O-:9])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:10]([OH:17])(=[O:16])/[CH:11]=[CH:12]\[C:13]([OH:15])=[O:14]>C(OCC)(=O)C>[C:10]([OH:17])(=[O:16])/[CH:11]=[CH:12]\[C:13]([OH:15])=[O:14].[C:1]([OH:9])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

参加物

4

反応物 2

HCID 242BenzoateHCID 444266Maleic Acid

生成物 1

HCID 68560292Benzoate maleate

試薬・触媒・溶媒 1

HCID 8857Ethyl Acetate溶媒

実験手順

In 3 mL of ethyl acetate was dissolved 0.25 g of 1-{3-[2-(1-benzothiophen-5-yl)ethoxy]propyl}-3-azetidinyl=benzoate, and 0.07 g of maleic acid was added thereto, after which the resulting mixture was heated to effect dissolution. The reaction mixture was cooled and the crystals precipitated were collected by filtration to obtain 0.15 g of 1-{3-[2-(1-benzothiophen-5-yl)ethoxy]propyl}-3-azetidinyl=benzoate maleate.

後処理

  1. additionwas added
  2. temperatureafter which the resulting mixture was heated
  3. dissolutiondissolution
  4. temperatureThe reaction mixture was cooled
  5. customthe crystals precipitated
  6. filtrationwere collected by filtration

出典と根拠

ORDレコード
ord-595bfc092f2a49439306456243cac199
出典データセット
uspto-grants-2006_08
特許番号
US07087594B2

関連ノート

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