Benzoate → Benzoate maleate
反応式
[C:1]([O-:9])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:10]([OH:17])(=[O:16])/[CH:11]=[CH:12]\[C:13]([OH:15])=[O:14]>C(OCC)(=O)C>[C:10]([OH:17])(=[O:16])/[CH:11]=[CH:12]\[C:13]([OH:15])=[O:14].[C:1]([OH:9])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1参加物
4
実験手順
In 3 mL of ethyl acetate was dissolved 0.25 g of 1-{3-[2-(1-benzothiophen-5-yl)ethoxy]propyl}-3-azetidinyl=benzoate, and 0.07 g of maleic acid was added thereto, after which the resulting mixture was heated to effect dissolution. The reaction mixture was cooled and the crystals precipitated were collected by filtration to obtain 0.15 g of 1-{3-[2-(1-benzothiophen-5-yl)ethoxy]propyl}-3-azetidinyl=benzoate maleate.
後処理
- additionwas added
- temperatureafter which the resulting mixture was heated
- dissolutiondissolution
- temperatureThe reaction mixture was cooled
- customthe crystals precipitated
- filtrationwere collected by filtration
出典と根拠
- ORDレコード
- ord-595bfc092f2a49439306456243cac199
- 出典データセット
- uspto-grants-2006_08
- 特許番号
- US07087594B2
反応ノート
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