反応式
[NH2:1][C:2]1[CH:3]=[CH:4][C:5]2[C:6]3[C:11]([C:12](=[O:16])[NH:13][C:14]=2[CH:15]=1)=[CH:10][C:9]([NH2:17])=[CH:8][CH:7]=3.P(Cl)(Cl)(Cl)=O.[CH:23]([N:25]1[CH2:29][CH2:28][CH2:27][CH2:26]1)=O.C(Cl)(Cl)Cl.CO>O1CCCC1>[N:25]1([CH:23]=[N:1][C:2]2[CH:3]=[CH:4][C:5]3[C:6]4[C:11]([C:12](=[O:16])[NH:13][C:14]=3[CH:15]=2)=[CH:10][C:9]([N:17]=[CH:23][N:25]2[CH2:29][CH2:28][CH2:27][CH2:26]2)=[CH:8][CH:7]=4)[CH2:29][CH2:28][CH2:27][CH2:26]1参加物
6
実験手順
A suspension of 3,8-diamino-6-(5H)-phenanthridone (500 mg) in tetrahydrofuran (5 ml) was added to a mixture of phosphorus oxychloride (0.75 ml) and N-formylpyrrolidine (2.5 ml) and tetrahydrofuran (5 ml), the temperature of the mixture being kept at 5° C. The resulting mixture was stirred for 30 minutes at room temperature, heated at 50° C. for 1 hour and worked as described in Example 8, paragraph 1. Yield 52%, melting point 280° C. (decomposition) (CHCl3 /methanol).
後処理
- custombeing kept at 5° C
- temperatureheated at 50° C. for 1 hour
出典と根拠
- ORDレコード
- ord-72abbf7032ed4faa95680a74f33b4c58
- 出典データセット
- uspto-grants-1986_07
- 特許番号
- US04599409
関連ノート
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