6-Nitroveratryl alcohol → 4,5-Dimethoxy-2-nitrobenzyl hexadecanesulfonate

HRID 745714

反応式

HRID 745714 の反応式
[CH3:1][O:2][C:3]1[C:10]([O:11][CH3:12])=[CH:9][C:6]([CH2:7][OH:8])=[C:5]([N+:13]([O-:15])=[O:14])[CH:4]=1.[CH2:16]([S:32](Cl)(=[O:34])=[O:33])[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31]>CC(C)=O.C1(NC2CCCCC2)CCCCC1>[CH2:16]([S:32]([O:8][CH2:7][C:6]1[CH:9]=[C:10]([O:11][CH3:12])[C:3]([O:2][CH3:1])=[CH:4][C:5]=1[N+:13]([O-:15])=[O:14])(=[O:34])=[O:33])[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31]

参加物

5

反応物 2

HCID 660976-Nitroveratryl alcoholHCID 969231-Hexadecanesulfonyl chloride

生成物 1

HCID 537926464,5-Dimethoxy-2-nitrobenzyl hexadecanesulfonate

試薬・触媒・溶媒 2

HCID 180Acetone溶媒HCID 7582Dicyclohexylamine溶媒

実験手順

To a solution of 5.33 g (0.025 mol) of 4,5-dimethoxy-2-nitrobenzyl alcohol and 8.15 g (0.025 mol) hexadecanesulfonyl chloride in 100 ml of acetone, dicyclohexylamine (5 ml, slight excess) was added via motor driven syringe over 30 minutes. After the addition was complete, the reaction was stirred an additional 30 minutes. The precipitated dicyclohexylamine hydrochloride was removed by filtration and the acetone filtrate reduced in volume in vacuo until most of the product had precipitated (yield 9.5 g, m.p. 81°-82° C.).

後処理

  1. customover 30 minutes
  2. additionAfter the addition
  3. customThe precipitated dicyclohexylamine hydrochloride was removed by filtration
  4. customhad precipitated (yield 9.5 g, m.p. 81°-82° C.)

出典と根拠

ORDレコード
ord-9e924dbf4a46448bbd2294eb5b08842e
出典データセット
uspto-grants-1986_07
特許番号
US04599273

関連ノート

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