Hexamethylenediamine → N-(6-aminohexyl)-aminomethanephosphonic acid monohydrate
反応式
Cl[CH2:2][P:3]([OH:6])(=[O:5])[OH:4].[NH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][NH2:14]>O>[OH2:4].[NH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][NH:14][CH2:2][P:3]([OH:6])(=[O:5])[OH:4]参加物
4
実験手順
Chloromethanephosphonic acid (6.5 g, 49.8 mmoles) and 1.6-diaminohexane (34.8 g, 300 mmoles) were dissolved in water (130 cm3) and heated under reflux for 20 hours. The water was removed and ethanol (250 cm3) was added to the solid residue. The phosphonic acid was filtered off and dried. The crude yield was 10.4 g (92%). A sample was purified by recrystallization from water/ethanol to give N-(6-aminohexyl)-aminomethanephosphonic acid monohydrate as a fine white crystalline solid having a melting point of 235° C.
後処理
- temperatureheated
- temperatureunder reflux for 20 hours
- customThe water was removed
- additionethanol (250 cm3) was added to the solid residue
- filtrationThe phosphonic acid was filtered off
- customdried
- customA sample was purified by recrystallization from water/ethanol
出典と根拠
- ORDレコード
- ord-1f74a984e1044d61a0a328a35fa3b720
- 出典データセット
- uspto-grants-1986_07
- 特許番号
- US04600429
反応ノート
読み込み中…