Acetic Anhydride → HCID 13375747、化合物
反応式
[CH3:1][O:2][C:3]([C:5]1[CH:22]=[CH:21][C:8]([C:9]2[O:10][C:11]3[C:16]([C:17](=[O:19])[CH:18]=2)=[CH:15][CH:14]=[C:13]([NH2:20])[CH:12]=3)=[CH:7][CH:6]=1)=[O:4].[C:23](OC(=O)C)(=[O:25])[CH3:24]>N1C=CC=CC=1>[C:23]([NH:20][C:13]1[CH:12]=[C:11]2[C:16]([C:17](=[O:19])[CH:18]=[C:9]([C:8]3[CH:21]=[CH:22][C:5]([C:3]([O:2][CH3:1])=[O:4])=[CH:6][CH:7]=3)[O:10]2)=[CH:15][CH:14]=1)(=[O:25])[CH3:24]参加物
4
実験手順
The mixture consisting of 2 g of 7-amino-4'-flavonecarboxylic acid methyl ester thus prepared, 30 cc of pyridine, 15 cc of acetic anhydride is heated at 40° for 2 hours with stirring. Completion of the reaction is verified by thin-layer chromatography (benzene (90)-dioxane (25)-acetic acid (4) elution solvent). The reaction mixture is poured in 500 cc of ice water. The solid that is formed is filtered, washed with water and dried by formation of an azeotropic system with benzene. Yield 56%.