Allyl bromide → 4-(allyloxy)-3-ethoxybenzaldehyde

HRID 746330ノート

反応式

HRID 746330 の反応式
[O:1]=[CH:2][C:3]1[CH:12]=[CH:11][C:9]([OH:10])=[C:5]([O:6][CH2:7][CH3:8])[CH:4]=1.[CH2:13](Br)[CH:14]=[CH2:15].C(=O)([O-])[O-].[K+].[K+]>CC(C)=O>[CH2:7]([O:6][C:5]1[CH:4]=[C:3]([CH:12]=[CH:11][C:9]=1[O:10][CH2:15][CH:14]=[CH2:13])[CH:2]=[O:1])[CH3:8]

参加物

5

反応物 3

HCID 7841Allyl bromideHCID 8467EthylvanillinHCID 11430Potassium Carbonate

生成物 1

HCID 35257364-(allyloxy)-3-ethoxybenzaldehyde

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

Ethyl vanillin (21.6 g, 0.130 mol) and allyl bromide (19.9 g, 0.160 mol) were heated under reflux together with potassium carbonate (27.3 g, 0.200 mol) in 150 ml acetone (abs.) for 8 hours. After cooling, the solid was filtered off and washed with acetone. A yellow oil was obtained after a thorough concentration of the organic phases.

後処理

  1. temperatureAfter cooling
  2. filtrationthe solid was filtered off
  3. washwashed with acetone
  4. customA yellow oil was obtained
  5. concentrationafter a thorough concentration of the organic phases

出典と根拠

ORDレコード
ord-90a5edfca4904f35b1b810a6754cd3bb
出典データセット
uspto-grants-2008_07
特許番号
US07393367B2

反応ノート

読み込み中…