Trifluoroacetic acid → HCID 69147864、化合物
反応式
[OH:1][CH:2]1[C:6]2([CH2:11][CH2:10][N:9](C(OC(C)(C)C)=O)[CH2:8][CH2:7]2)[O:5][CH2:4][CH2:3]1.[F:19][C:20]([F:25])([F:24])[C:21]([OH:23])=[O:22]>ClCCl>[F:19][C:20]([F:25])([F:24])[C:21]([OH:23])=[O:22].[OH:1][CH:2]1[C:6]2([CH2:11][CH2:10][NH:9][CH2:8][CH2:7]2)[O:5][CH2:4][CH2:3]1参加物
4
実験手順
tert-Butyl 4-hydroxy-1-oxa-8-azaspiro[4.5]decane-8-carboxylate (from step (iii) above; 300 mg) was dissolved in dichloromethane and trifluoroacetic acid (2 mL) was added. The solution was stirred for 2 h and was concentrated in vacuo to afford the product as a colorless oil.
後処理
- concentrationwas concentrated in vacuo
出典と根拠
- ORDレコード
- ord-16bd56e72b6c4f89907764f89e395b12
- 出典データセット
- uspto-grants-2008_07
- 特許番号
- US07393858B2
反応ノート
読み込み中…