Acrylonitrile → n,n-Bis(2-cyanoethyl)hexylamine

HRID 74710

反応式

HRID 74710 の反応式
[C:1](#[N:4])[CH:2]=[CH2:3].[CH2:5]([NH2:11])[CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]>>[C:1]([CH2:2][CH2:3][N:11]([CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10])[CH2:3][CH2:2][C:1]#[N:4])#[N:4]

参加物

3

反応物 2

HCID 7855AcrylonitrileHCID 8102Hexylamine

生成物 1

HCID 16733110n,n-Bis(2-cyanoethyl)hexylamine収率 98.9%

反応条件

温度
70 °C

実験手順

20.1 g of acrylonitrile was added dropwise to an aqueous solution (150 ml) of 15.5 g of hexylamine at room temperature over 0.5 hours, and then the mixed solution was stirred at 70° C. for 3 hours. After standing to cool to room temperature, the mixed solution was extracted with 150 ml of ethyl acetate. The organic layer was separated from the solution, dried over anhydrous magnesium sulfate, and distilled off the solvent to obtain 31.4 g of a target compound as a colorless oily product.

後処理

  1. temperatureto cool to room temperature
  2. extractionthe mixed solution was extracted with 150 ml of ethyl acetate
  3. customThe organic layer was separated from the solution
  4. dry with materialdried over anhydrous magnesium sulfate
  5. distillationdistilled off the solvent

出典と根拠

ORDレコード
ord-0d4eab3b0e8f40d185c25da15d7077e2
出典データセット
uspto-grants-2014_09
特許番号
US08830811B2

関連ノート

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