Trifluoroacetate → HCID 11644225、化合物
反応式
C([O:8][C:9]1[C:10]([O:22][CH3:23])=[CH:11][C:12]([C:20]#[N:21])=[C:13]([N:15]=[CH:16][N:17]([CH3:19])[CH3:18])[CH:14]=1)C1C=CC=CC=1.FC(F)(F)C([O-])=O>FC(F)(F)C(O)=O>[C:20]([C:12]1[CH:11]=[C:10]([O:22][CH3:23])[C:9]([OH:8])=[CH:14][C:13]=1[N:15]=[CH:16][N:17]([CH3:18])[CH3:19])#[N:21]参加物
4
実験手順
N′-(5-(benzyloxy)-2-cyano-4-methoxyphenyl)-N,N-dimethylimidoformamide (110 g, 356 mmol) and trifluoroacetic acid (600 ml) were heated at reflux for 15 minutes. The reaction was evaporated in vacuo and then azeotroped with toluene. The residue was triturated with diethyl ether and the solid collected by suction filtration. The solid was dried in vacuo to yield N′-(2-cyano-5-hydroxy-4-methoxyphenyl)-N,N-dimethylimidoformamide (112 g, 95% yield) as a light brown trifluoroacetate salt: